產品詳情
簡單介紹：
Anti-FNBP1L antibody (STJA0004478)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Formin-Binding Protein 1-Like is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 0.9 mg/mL |
| Dilution Range: | WB 1:500-1:2000, IHC 1:20-1:100 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | FNBP1L |
| Gene ID: | 54874 |
| Uniprot ID: | FBP1L_HUMAN |
| Immunogen: | Synthetic peptide of human FNBP1L |
| Function | Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. |
| Protein Name | Formin-Binding Protein 1-Like Transducer Of Cdc42-Dependent Actin Assembly Protein 1 Toca-1 |
| Database Links | Reactome: R-HSA-8856828 Reactome: R-HSA-9013148 Reactome: R-HSA-9013409 |
| Cellular Localisation | Cytoplasm Cytoskeleton Cell Cortex Cytoplasmic Vesicle Cell Membrane Peripheral Membrane Protein Cytoplasmic Side |
| Alternative Antibody Names | Anti-Formin-Binding Protein 1-Like antibody Anti-Transducer Of Cdc42-Dependent Actin Assembly Protein 1 antibody Anti-Toca-1 antibody Anti-FNBP1L antibody Anti-C1orf39 antibody Anti-TOCA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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