產品詳情
簡單介紹：
Anti-FNTA antibody (280-379) (STJ111424)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FNTA (280-379) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FNTA |
| Gene ID: | 2339 |
| Uniprot ID: | FNTA_HUMAN |
| Immunogen Region: | 280-379 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-379 of human FNTA (NP_002018.1). |
| Immunogen Sequence: | LKGILQDRGLSKYPNLLNQL LDLQPSHSSPYLIAFLVDIY EDMLENQCDNKEDILNKALE LCEILAKEKDTIRKEYWRYI GRSLQSKHSTENDSPTNVQQ |
| Post Translational Modifications | Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA. |
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
| Protein Name | Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha Caax Farnesyltransferase Subunit Alpha Ftase-Alpha Ras Proteins Prenyltransferase Subunit Alpha Type I Protein Geranyl-Geranyltransferase Subunit Alpha Ggtase-I-Alpha |
| Database Links | Reactome: R-HSA-111465 Reactome: R-HSA-2514859 Reactome: R-HSA-9648002 Reactome: R-HSA-9679191 |
| Alternative Antibody Names | Anti-Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha antibody Anti-Caax Farnesyltransferase Subunit Alpha antibody Anti-Ftase-Alpha antibody Anti-Ras Proteins Prenyltransferase Subunit Alpha antibody Anti-Type I Protein Geranyl-Geranyltransferase Subunit Alpha antibody Anti-Ggtase-I-Alpha antibody Anti-FNTA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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