產品詳情
簡單介紹:
Anti-FOXD3 antibody (211-260 aa) (STJ93108)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Forkhead box protein D3 (211-260 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FOXD3 |
Gene ID: | 27022 |
Uniprot ID: | FOXD3_HUMAN |
Immunogen Region: | 211-260 aa |
Specificity: | FoxD3 Polyclonal Antibody detects endogenous levels of FoxD3 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human FOXD3 at the amino acid range 211-260 |
Function | Binds to the consensus sequence 5'-AATTAGTTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Negatively regulates transcription of transcriptional repressor RHIT/ZNF205. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. |
Protein Name | Forkhead Box Protein D3 Hnf3/Fh Transcription Factor Genesis |
Database Links | Reactome: R-HSA-2892247 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Forkhead Box Protein D3 antibody Anti-Hnf3/Fh Transcription Factor Genesis antibody Anti-FOXD3 antibody Anti-HFH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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