Anti-FPR1 antibody (151-200 aa) (STJ93134) STJ93134|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-FPR1 antibody (151-200 aa) (STJ93134)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-fMet-Leu-Phe receptor (151-200 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:40000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FPR1
Gene ID:	2357
Uniprot ID:	FPR1_HUMAN
Immunogen Region:	151-200 aa
Specificity:	FPR1 Polyclonal Antibody detects endogenous levels of FPR1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human FPR1 at the amino acid range 151-200

Post Translational Modifications	Phosphorylated.which is necessary for desensitization.
Function	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Protein Name	Fmet-Leu-Phe Receptor Fmlp Receptor N-Formyl Peptide Receptor Fpr N-Formylpeptide Chemoattractant Receptor
Database Links	Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Internalizes In Presence Of Its Ligands Fmlp Tafa4 And Ctsg
Alternative Antibody Names	Anti-Fmet-Leu-Phe Receptor antibody Anti-Fmlp Receptor antibody Anti-N-Formyl Peptide Receptor antibody Anti-Fpr antibody Anti-N-Formylpeptide Chemoattractant Receptor antibody Anti-FPR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-FPR1 antibody (151-200 aa) (STJ93134)