產品詳情
簡單介紹:
Anti-FPR2 antibody (130-210 aa) (STJ192622)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse/Swine |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-N-formyl peptide receptor 2 (130-210 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FPR2 |
Gene ID: | 2358 |
Uniprot ID: | FPR2_HUMAN |
Immunogen Region: | 130-210 aa |
Specificity: | FPR2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 130-210 |
Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of pro-inflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. Acts as a receptor for humanin. |
Protein Name | N-Formyl Peptide Receptor 2 Fmlp-Related Receptor I Fmlp-R-I Formyl Peptide Receptor-Like 1 Hm63 Lipoxin A4 Receptor Lxa4 Receptor Rfp |
Database Links | Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Associates With Amyloid-Beta Protein 42 Product Of App At The Cell Surface And The Complex Is Then Rapidly Internalized Also Internalized In The Presence Of Humanin |
Alternative Antibody Names | Anti-N-Formyl Peptide Receptor 2 antibody Anti-Fmlp-Related Receptor I antibody Anti-Fmlp-R-I antibody Anti-Formyl Peptide Receptor-Like 1 antibody Anti-Hm63 antibody Anti-Lipoxin A4 Receptor antibody Anti-Lxa4 Receptor antibody Anti-Rfp antibody Anti-FPR2 antibody Anti-FPRH1 antibody Anti-FPRL1 antibody Anti-LXA4R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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