產品詳情
簡單介紹：
Anti-FPR2 antibody (STJ11104999)
詳情介紹：
| Host: | Rabbit |
| Applications: | IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-N-Formyl Peptide Receptor 2 is suitable for use in Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FPR2 |
| Gene ID: | 2358 |
| Uniprot ID: | FPR2_HUMAN |
| Immunogen: | Recombinant protein of human FPR2. |
| Tissue Specificity | Detected in lung, bone marrow, neutrophils, spleen and testis. |
| Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of pro-inflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. Acts as a receptor for humanin. |
| Protein Name | N-Formyl Peptide Receptor 2 Fmlp-Related Receptor I Fmlp-R-I Formyl Peptide Receptor-Like 1 Hm63 Lipoxin A4 Receptor Lxa4 Receptor Rfp |
| Database Links | Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Associates With Amyloid-Beta Protein 42 Product Of App At The Cell Surface And The Complex Is Then Rapidly Internalized Also Internalized In The Presence Of Humanin |
| Alternative Antibody Names | Anti-N-Formyl Peptide Receptor 2 antibody Anti-Fmlp-Related Receptor I antibody Anti-Fmlp-R-I antibody Anti-Formyl Peptide Receptor-Like 1 antibody Anti-Hm63 antibody Anti-Lipoxin A4 Receptor antibody Anti-Lxa4 Receptor antibody Anti-Rfp antibody Anti-FPR2 antibody Anti-FPRH1 antibody Anti-FPRL1 antibody Anti-LXA4R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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