產品詳情
簡單介紹：
Anti-FCGR2A antibody (34-316) (STJ23641)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FCGR2A (34-316) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCGR2A |
| Gene ID: | 2212 |
| Uniprot ID: | FCG2A_HUMAN |
| Immunogen Region: | 34-316 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 34-316 of human FCGR2A (NP_001129691.1). |
| Immunogen Sequence: | QAAAPPKAVLKLEPPWINVL QEDSVTLTCQGARSPESDSI QWFHNGNLIPTHTQPSYRFK ANNNDSGEYTCQTGQTSLSD PVHLTVLSEWLVLQTPHLEF QEGETIMLRCHSWKDKPLVK VTFFQNGKSQKFSHLDPTFS IPQANHSHSGDYHCTGNIGY TLFSSKPVTITVQVPSMGSS SPMGIIVAVVIATAVAAIVA AVVALIYCRKKRISANSTDP VKAAQFEPPGRQMIAIRKR |
| Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A antibody Anti-Igg Fc Receptor Ii-A antibody Anti-Cdw32 antibody Anti-Fc-Gamma Rii-A antibody Anti-Fc-Gamma-Riia antibody Anti-Fcrii-A antibody Anti-Cd Antigen Cd32 antibody Anti-FCGR2A antibody Anti-CD32 antibody Anti-FCG2 antibody Anti-FCGR2A1 antibody Anti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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