產品詳情
簡單介紹:
Anti-FGF2 antibody (100-200) (STJ11104323)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Fibroblast Growth Factor 2 (100-200) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:5000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FGF2 |
Gene ID: | 2247 |
Uniprot ID: | FGF2_HUMAN |
Immunogen Region: | 100-200 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5). |
Immunogen Sequence: | RAPERVGGRGRGRGTAAPRA APAARGSRPGPAGTMAAGSI TTLPALPEDGGSGAFPPGHF KDPKRLYCKNGGFFLRIHPD GRVDGVREKSDPHIKLQLQA E |
Tissue Specificity | Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue. |
Post Translational Modifications | Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion. Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing. |
Function | Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. |
Protein Name | Fibroblast Growth Factor 2 Fgf-2 Basic Fibroblast Growth Factor Bfgf Heparin-Binding Growth Factor 2 Hbgf-2 |
Database Links | Reactome: R-HSA-109704 Reactome: R-HSA-1257604 Reactome: R-HSA-1839122 Reactome: R-HSA-1839130 Reactome: R-HSA-190322 Reactome: R-HSA-190370 Reactome: R-HSA-190372 Reactome: R-HSA-190373 Reactome: R-HSA-190375 Reactome: R-HSA-190377 Reactome: R-HSA-2033519 Reactome: R-HSA-2219530 Reactome: R-HSA-2892247 Reactome: R-HSA-3000170 Reactome: R-HSA-3000171 Reactome: R-HSA-5654219 Reactome: R-HSA-5654221 Reactome: R-HSA-5654227 Reactome: R-HSA-5654228 Reactome: R-HSA-5654687 Reactome: R-HSA-5654688 Reactome: R-HSA-5654689 Reactome: R-HSA-5654693 Reactome: R-HSA-5654695 Reactome: R-HSA-5654699 Reactome: R-HSA-5654700 Reactome: R-HSA-5654704 Reactome: R-HSA-5654706 Reactome: R-HSA-5654710 Reactome: R-HSA-5654712 Reactome: R-HSA-5654719 Reactome: R-HSA-5654720 Reactome: R-HSA-5654726 Reactome: R-HSA-5654727 Reactome: R-HSA-5654732 Reactome: R-HSA-5654733 Reactome: R-HSA-5655253 Reactome: R-HSA-5655302 Reactome: R-HSA-5655332 Reactome: R-HSA-5658623 Reactome: R-HSA-5673001 Reactome: R-HSA-6785807 Reactome: R-HSA-6811558 Reactome: R-HSA-8851708 Reactome: R-HSA-9761174 |
Cellular Localisation | Secreted Nucleus Exported From Cells By An Endoplasmic Reticulum (Er)/Golgi-Independent Mechanism Unconventional Secretion Of Fgf2 Occurs By Direct Translocations Across The Plasma Membrane Binding Of Exogenous Fgf2 To Fgfr Facilitates Endocytosis Followed By Translocations Of Fgf2 Across Endosomal Membrane Into The Cytosol Nuclear Import From The Cytosol Requires The Classical Nuclear Import Machinery Involving Proteins Kpna1 And Kpnb1 As Well As Cep57 |
Alternative Antibody Names | Anti-Fibroblast Growth Factor 2 antibody Anti-Fgf-2 antibody Anti-Basic Fibroblast Growth Factor antibody Anti-Bfgf antibody Anti-Heparin-Binding Growth Factor 2 antibody Anti-Hbgf-2 antibody Anti-FGF2 antibody Anti-FGFB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
相關信息

- 細胞培養玄學-MRC-5細胞 2025-01-07
- Ocean NanoTech定製的詳細步驟 2021-10-31
- click chemistry tools數據結果比... 2021-10-31
- LaysanBio代理商相關文獻資料2020 2021-10-31
- Abbiotec代理的產品得到重複驗證2020 2021-10-31
- zyagen Laboratories代理的產品得到... 2021-06-20
- Toxin Technologies代理商相關文獻資... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理biocolor公司試劑產品... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理cytognos公司試劑產品... 2021-03-14
- Gelest代理的產品得到重複驗證2020 2021-03-14