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Anti-MAP2K3 antibody (1-70) (STJ110029) STJ110029|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-MAP2K3 antibody (1-70) (STJ110029)

  • 產品型號：STJ110029
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-MAP2K3 antibody (1-70) (STJ110029)
詳情介紹：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MAP2K3 (1-70) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAP2K3
Gene ID: 5606
Uniprot ID: MP2K3_HUMAN
Immunogen Region: 1-70
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human MEK3 (NP_659731.1).
Immunogen Sequence: MESPASSQPASMPQSKGKSK RKKDLRISCMSKPPAPNPTP PRNLDSRTFITIGDRNFEVE ADDLVTISEL
Tissue Specificity Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Post Translational Modifications Autophosphorylated. Phosphorylation on Ser-218 and Thr-222 by MAP kinase kinase kinases regulates positively the kinase activity. Phosphorylated by TAOK2. (Microbial infection) Yersinia YopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway.
Function Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
Protein Name Dual Specificity Mitogen-Activated Protein Kinase Kinase 3
Map Kinase Kinase 3
Mapkk 3
Mapk/Erk Kinase 3
Mek 3
Stress-Activated Protein Kinase Kinase 2
Sapk Kinase 2
Sapkk-2
Sapkk2
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-450302
Reactome: R-HSA-5210891 P46734-3
Alternative Antibody Names Anti-Dual Specificity Mitogen-Activated Protein Kinase Kinase 3 antibody
Anti-Map Kinase Kinase 3 antibody
Anti-Mapkk 3 antibody
Anti-Mapk/Erk Kinase 3 antibody
Anti-Mek 3 antibody
Anti-Stress-Activated Protein Kinase Kinase 2 antibody
Anti-Sapk Kinase 2 antibody
Anti-Sapkk-2 antibody
Anti-Sapkk2 antibody
Anti-MAP2K3 antibody
Anti-MEK3 antibody
Anti-MKK3 antibody
Anti-PRKMK3 antibody
Anti-SKK2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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